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Harnessing the healing power of light
Part 1: What you need to know about UV rays—beyond sunburn

by Dr. Jonathan V. Wright, MD

References

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  2. Kujundzic E, Matalkah F, Howard CJ, et al. “UV air cleaners and upper-room air ultraviolet germicidal irradiation for controlling airborne bacteria and fungal spores.” J Occup Environ Hyg 2006; 3(10): 536-546
  3. Ritter MA, Olberding EM, Malinzak RA. “Ultraviolet lighting during orthopaedic surgery and the rate of infection.” J Bone Joint Surg Am 2007; 89(9): 1,935-1,940
  4. Miner AL, Losina E, Katz JN, et al. “Infection control practices to reduce airborne bacteria during total knee replacement: a hospital survey in four states.” Infect Control Hosp Epidemiol 2005; 26(12): 910-915
  5. Kujundzic E, Matalkah F, Howard CJ, et al. “UV air cleaners and upper-room air ultraviolet germicidal irradiation for controlling airborne bacteria and fungal spores.” J Occup Environ Hyg 2006; 3(10): 536-546
  6. Ritter MA, Olberding EM, Malinzak RA. “Ultraviolet lighting during orthopaedic surgery and the rate of infection.” J Bone Joint Surg Am 2007; 89(9): 1,935-1,940
  7. Koek M, Buskens E, Steegmans P, et al. “UVB phototherapy in an outpatient setting or at home: a pragmatic randomized single-blind trial designed to settle the dispute. The Pluto study.” BMC Med Res Methodol 2006; 6: 39
  8. Silva SH, Guedes ACM, Gontijo B, et al. “Influence of narrow-band UVB phototherapy on cutaneous microbiota of children with atopic dermatitis.” Journal of the European Academy of Dermatology and Venereology 2006; 20(9): 1,114-1,120
  9. Marshall S. “Technology insight: ECP for the treatment of GvHD – can we offer selective immune control without generalized immunosuppression?” Nature Clinical Practice Oncology 2006; 3: 302-314
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  11. Kumar V, Lockerbie O, Keil SD, et al. “Riboflavin and UV-light based pathogen reduction: extent and consequence of DNA damage at the molecular level.” Photochem Photobiol 2004; 80: 15-21
  12. Edelson R, Berger C, Gasparro F, et al. “Treatment of cutaneous T-cell lymphoma by extracorporeal photochemotherapy. Preliminary results.” NEJM 1987; 316: 297-303
  13. Vowels BR, Cassin M, Boufal MH, et al. “Extracorporeal photochemotherapy induces the production of tumor necrosis factor-α by monocytes: implications for the treatment of cutaneous T-cell lymphoma and systemic sclerosis.” Journal of Investigative Dermatology 1992; 98: 686-692.
  14. Potashov LV, Cheminava RV. “Reinfusion of the patient’s own irradiated blood in surgical patients.” Vestn Khir Im II Grek 1980; 125(10): 144-146
  15. Boudurov N, Filipov ZH. “Effect of ultraviolet ray-irradiated autogenous blood on hematological indices in horses.” Vet Med Nauki 1976; 13(10):11-19.
  16. Ivanov EM, Shakirova OV, Zhurayskaia NS. “Use of auto-transfusion of UV-irradiated blood in chronic bronchitis.” Klin Med (Mosk) 2002; 80(6): 21-25
  17. Paleev NR, Vetchinnikov ON, Plaksina GV, Brucheeva IS. “The efficacy of the extracorporeal ultraviolet irradiation of autologous blood in the treatment of chronic nonspecific lung diseases.” Vestn Ross Akad Med Nauk 1993; 3: 3-6
  18. Kuvshinchikova VN, Shmelev EI, Mishin VI. “Effectiveness of extracorporeal ultraviolet blood irradiation in treatment of chronic obstructive bronchitis in pulmonary tuberculosis.” Probl Tuberk 1998; 3: 48-50
  19. Isaev IuV, Dzhangirova GM, Padenko AV, Lipikin AA. “Use of UV autologous blood irradiation for preventing the occurrence of tracheobronchitis during tracheostomy.” Vestn Khir Im II Grek 1987; 138(4):116-118
  20. McGlade JP, Gorman S, Zosky GR, et al. “Suppression of the asthmatic phenotype by ultraviolet B-induced, antigen-specific regulatory cells.” Clinical & Experimental Allergy 2007; 37(9): 1,267–1,276
  21. Bernstein JA, Bobbitt RC, Levin L, et al. “Health effects of ultraviolet irradiation in asthmatic children’s homes.” Journal of Asthma 2006; 43: 255-262
  22. Alizade IG, Karaeva NT. “Experience in the use of auto-transfusions of laser-irradiated blood in treating hypertension patients.” Lik Sprava 1994; May-Jun(5-6): 29-32
  23. Paleev NR, Cherniakov VL, Vetchinnikova ON. “Ultraviolet irradiation of the blood in the treatment of pyo-inflammatory complications in patients with terminal renal failure.” Vestn Akad Med Nauk SSSR 1991; 3: 15-20
  24. Gaiseniuk LA. “Use of re-infusions of isolated irradiated auto-blood for the correction of hematopoietic disorders.” Med Radiol (Mosk) 1987; 32(11): 15-18
  25. Hansen E, Knuechel E, Altmeppen J, Taeger K. “Blood irradiation for intraoperative auto-transfusion in cancer surgery: demonstration of efficient elimination of contaminating tumor cells.” Transfusion 1999; 39(6): 608-615
  26. Hansen E, Bechmann V, Altmeppen J. “Intraoperative blood salvage in cancer surgery: safe and effective?” Transfus Apher Sci 2002; 27(2): 153-157
  27. Sawyer L, Hanson D, Castro G, et al. “Inactivation of parvovirus B19 in human platelet concentrates by treatment with amotosalen and ultraviolet A illumination.” Transfusion 2007; 47(6): 1,062-1,070.
  28. Thai TP, Houghton PE, Campbell KE, Woodbury MG. “Ultraviolet light C in the treatment of chronic wounds with MRSA: a case study.” Ostomy Wound Manage 2002; 48(11): 52-60
  29. Thai TP, Keast DH, Campbell KE, et al. “Effect of ultraviolet light C on bacterial colonization in chronic wounds.” Ostomy Wound Manage 2005; 51(10): 32-45.
  30. Conner-Kerr TA, Sullivan PK, Gaillard J, et al. “The effects of ultraviolet radiation on antibiotic-resistant bacteria in vitro.” Ostomy Wound Manage 1998; 44(10): 50-6.
  31. Phoenix DA, Harris F. “Light activated compounds as antimicrobial agents—patently obvious?” Recent Patents Anti-Infect Drug Disc 2006; 1(2): 181-99.

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